Mouse Developmental Methylome Database

DevMouse is the mouse developmental methylome database which focuses on the efficient storage of DNA methylomes in temporal order and quantitative analysis of methylation dynamics during mouse development. The flexible query engine can be used for acquisition of methylation profiles for genes, miRNAs, LncRNAs, genomic intervals of interest across selected developmental stages. DevMouse offers online analysis tools for quantification of methylation variation, identification of differentially methylated genes, hierarchical clustering, gene function annotation and enrichment. The configurable MethyBrowser can view the base-resolution methylomes under genomic context. All the search and analysis results can be downloaded for further analysis. In brief, DevMouse hosts comprehensive mouse developmental methylome data and provides online tools to explore the relationships of DNA methylation and development, meanwhile offers useful reference for human development and disorders.

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